Liver fibrosis, non-parenchymal cells and the promise of exosome therapy

HMN 2024 – In response to chronic stimuli such as alcohol abuse, viral infection, NAFLD/NASH and toxic damage, liver loses its normal structure and non-parenchymal cells including HSCs, KCs and LSECs undergo phenotypic changes. HSCs and KCs are in activation and LSECs become capillarised with loss of fenestrae and markers followed by release of fibrogenic stimuli such as […]

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